Relative Oral Toxicity of Iron Preparations
نویسندگان
چکیده
منابع مشابه
Relative Oral Efficacy and Acute Toxicity of Hydroxypyridin-4-One Iron Chelators in Mice
The relationship between the oral efficacy and the acute toxicity of hydroxypyridin4one iron chelators has been investigated to clarify structure-function relationships of these compounds in vivo and to identify compounds with the maximum therapeutic safety margin. By comparing “Fe excretion following oral or intraperitoneal administration of increasing doses of each chelator to iron-overloaded...
متن کاملRelative oral efficacy and acute toxicity of hydroxypyridin-4-one iron chelators in mice.
The relationship between the oral efficacy and the acute toxicity of hydroxypyridin-4-one iron chelators has been investigated to clarify structure-function relationships of these compounds in vivo and to identify compounds with the maximum therapeutic safety margin. By comparing 59Fe excretion following oral or intraperitoneal administration of increasing doses of each chelator to iron-overloa...
متن کاملIron toxicity
During the past half century, excessive/misplaced iron has been observed to be a risk factor for an increasing number and diversity of disease conditions. An extensive list of conditions and of the types of iron association were published in early 2008. Within the subsequent year, four additional disorders have been recognized to be enhanced by iron: aging muscle atrophy, viral replication, ros...
متن کاملComparison Study of Oral Iron Preparations Using a Human Intestinal Model
Iron deficiency and related iron deficiency anaemia (IDA) are the most prevalent nutritional disorders worldwide. The standard treatment involves supplementation with solid or liquid iron supplement preparations, usually based on a ferrous salt such as ferrous sulphate, ferrous fumarate, or ferrous gluconate. In the present study, we compared iron uptake and absorption from various solid and li...
متن کاملI. Oral Intake Herbal Preparations
According to the reliability of therapeutic effects, Chinese medicinal herbs divide into 3 main categories. The first is the Classical Medicinal Herbs, including approximate 265 kinds of medicinal herbs and plants and a few of medicinal minerals that have been identified by scientific works and proven by clinic studies. The second is the folk herbs (folk experienced recipe herbs) that have appr...
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ژورنال
عنوان ژورنال: BMJ
سال: 1947
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.4518.201